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How high-protein diet can prevent, treat obesity

Washington D.C. [USA], Nov 7 (ANI): High protein diet contains an amino acid called phenylalanine that, according to a latest research, is a new hunger suppressant.
The study shows how phenylalanine reduces food intake by affecting the gut and the brain, and suggests that it may be used to prevent or treat obesity.
Although high protein diets have been shown to be satisfying and to promote weight loss, they can be hard to maintain and may lead to other health problems in the long-term.
Phenylalanine is an amino acid produced in the gut when protein is digested and has previously been shown to affect the release of gut hormones that reduce appetite in rodents.
However, it was unclear exactly how the amino acid was causing this release and whether other systems were involved in phenylalanine's appetite supressing effects.
To investigate the effects of phenylalanine on appetite and gut hormone release, Professor Kevin Murphy and colleagues at Imperial College London, examined the eff..

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6 Things Your Looks Say About Your Health

Got lackluster locks? Or a scaly patch on an elbow? Your body may be trying to tell you something. "There are huge links between how we appear on the outside and what's happening inside," says Ramsey Markus, MD, associate professor of dermatology at Baylor College of Medicine in Houston. Even the most common beauty woes, like brittle nails and a dull complexion, can hint at issues beneath the surface. Give yourself a once-over for these six superficial signs you should see your doctor.If you have: Thick, dark facial or body hairIt might mean: Polycystic ovary syndrome (PCOS). "We're not talking about a few wispy strands," says Zoe Stallings, MD, a family physician at Duke Medicine in Durham, N.C. "This is a thick coat of 'I have sideburns that tweezers can't handle' hair." It tends to sprout in places where men grow hair (like the cheeks, chin, chest and back) and may be due to elevated levels of male sex hormones—a common symptom of the endocrine disorder PCOS, which can increase your risk of infertility and diabetes. Ask your doc for a blood test. Birth control pills and lifestyle changes like losing excess weight (even just a few pounds) can reduce symptoms. Your MD might also prescribe a steroid to help correct the hormone imbalance or a cream that inhibits the growth of facial hair. Another option: talking to your dermatologist about laser hair removal. "The pro is that it's effective," Dr. Stallings says. "The con is the price." Each session costs around $300, though some insurance plans will cover the treatment.If you have: A brittle nailIt might mean: Fungus. It's disgusting but true—your nail bed is a perfect home for fungi. "They like having a warm, moist layer of skin to feed off," Dr. Markus explains. When a parasite moves in, your nail may start to split or crumble at the edges. A derm might prescribe medication. It may also help to limit exposure to moisture by wearing gloves to do the dishes or changing socks after a workout.If the nails on both hands are brittle, you can probably blame overzealous hand washing; a supplement could do the trick. Vitamins containing keratin, in particular, improve nail strength, according to a 2014 study.Related: Lifestyle Changes to Look YoungerIf you have: A scaly red patchIt might mean: Psoriasis. This rash isn't just a skin problem. Psoriasis is an autoimmune disorder that can crop up at any age and is linked to inflammation throughout the body (experts are unsure if psoriasis causes inflammation or vice versa). Lesions—typically on the scalp, elbows and knees—are a common symptom, but moderate to severe psoriasis is also connected to cardiovascular disease, according to a longitudinal study published last fall. Fortunately, "your risk of heart attack goes down when you treat a more severe case of psoriasis," says Jennifer Chen, MD, clinical assistant professor of dermatology at Stanford School of Medicine. See your derm: A variety of oral and topical meds, as well as phototherapy, can reduce outbreaks.If you have: Persistent acneIt might mean: A hormonal imbalance. Breakouts aren't just for teens and tweens. "Acne may recur during perimenopause," Dr. Chen explains. As estrogen and progesterone levels drop, your hormonal balance can tip toward testosterone, which triggers a surge in the production of pore-clogging oil. "Like menopause itself, this acne varies in duration and intensity," Dr. Chen says, though the pimples often appear on the jawline. The good news, Dr. Chen says: "We have great medications to prevent acne. You just have to be proactive about it."If you have: Dry, blotchy skinIt might mean: An omega-3 deficiency. "As we age, our sebaceous glands produce less oil that lubricates skin," says Valori Treloar, MD, co-author of The Clear Skin Diet. Omega-3 fatty acids help keep your complexion healthy-looking in part because they protect dry skin from developing inflammation. If you have a deficiency, your skin may become itchy and blotchy, Dr. Treloar says. Eat plenty of foods rich in omega-3s, like walnuts, flaxseed and cold water fish. Still worried you're not getting enough? Consider taking a fish oil supplement.If you have: Thinning hairIt might mean: Hypothyroidism. When your thyroid gland is underactive, too many of your hair follicles go into resting mode. As strands naturally shed, they aren't replaced, and "women start to notice that their scalp is showing," Dr. Stallings says. Synthetic hormones and other remedies can help. Another possible culprit: low estrogen. For women in menopause, a B complex multi with collagen may restore thinning tresses, Dr. Stallings says. If you've just had a baby (another cause of an estrogen dip), don't fret: Your hair's volume should return to normal by the time your little one is six months old.Related: 18 Style Mistakes That Age You

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5 Sleep Problems Nobody Talks About

You drift off at night like a newborn baby yet can't recall the last time you woke up truly refreshed. It may not seem that weird: "People tend to assume that because our modern lives are so hectic, nobody feels rested," says Meir Kryger, MD, a professor at the Yale School of Medicine. But the reality is, you might have a sleep disorder and not even know it. There are a handful of problems that can cheat you out of quality slumber, leaving you more tired in the morning than you were when you went to bed. Find out what could be going on between your sheets and how to catch more restorative z's, starting tonight.Sleep Problem No. 1: You snore like a sawThose snuffle-snorts mean that your slack tongue and throat muscles are narrowing your airway, possibly due to the shape of your soft palate or any extra weight you're carrying.Although you're likely to wake up if you get short of breath, it may not be for long enough to remember. Some people wake dozens or even hundreds of times a night—a disorder known as sleep apnea that increases the risk of heart disease, stroke and possibly osteoporosis, according to a new study in the Journal of Bone and Mineral Research. "Those repeated awakenings are as disruptive as someone pinching you every two minutes all night long," says Safwan Badr, MD, chief of the division of pulmonary, critical care and sleep medicine at Wayne State University School of Medicine in Detroit.Sleep aid: If you rarely wake up feeling bright-eyed, see a specialist to get checked for sleep apnea.(Three to 9 percent of women between the ages of 30 and 70 suffer from it.) If you have the condition, a CPAP machine and mask can help by keeping your pharynx open with a steady stream of air.To quiet your snore, avoid rolling onto your back—a position that makes your airway more likely to collapse. Rachel Salas, MD, associate professor of neurology at Johns Hopkins University School of Medicine, suggests this little trick: Sew a tennis ball into the pocket of a sweatshirt and wear it backward to bed.RELATED: 14 Reasons You're Always TiredSleep Problem No. 2: You grind your teethDo you wake up with a sore jaw or get chronic headaches? If so, you may be gnashing your ivories overnight. All that clenching can cause enough pain to interfere with your shut-eye (not to mention wear down your enamel). Experts believe that teeth grinding, which about 16 percent of us do, is associated with anxiety—though an abnormal bite and antidepressants can also play a role.Sleep aid: A dentist will fit you with a mouth guard. If you're clamping down because you're overwhelmed and overloaded, find a healthier way to manage stress, urges Michael A. Grandner, PhD, an instructor in psychiatry at the Perelman School of Medicine at the University of Pennsylvania. "It's also crucial to spend plenty of time winding down before bed so you drift off in a calm, relaxed state," he adds.RELATED: 11 Signs You're Sleep Deprived

Next Page: Sleep Problem No. 3: Your body clock is off

Sleep Problem No. 3: Your body clock is offNot even drowsy until the wee hours? Delayed sleep-phase syndrome (DSPS) is the technical term for this disorder, which afflicts 10 percent of people who seek help for insomnia. It involves a biological glitch that prevents your body from making melatonin (the sleep hormone) until 12 a.m. or later. A prime sign you've got DSPS: You've been a night owl since high school. The syndrome is common among teenagers and sometimes persists into adulthood. If you're not squeezing in at least seven hours of z's a night, you're at greater risk of high blood pressure and diabetes. What's more, a recent study published in Cognitive Therapy and Research found that people who nod off late (and get less sleep as a result) tend to experience more negative thoughts.Sleep aid: Begin by improving your sleep hygiene. Cut back on caffeine. Avoid tech and television starting 90 minutes before bedtime. Create a soothing wind-down routine. And get some sun first thing in the morning to help reset your body's 24-hour rhythm. "In 80 percent of cases, these strategies lead people to conk out earlier," Dr. Badr says. If they don't do the trick, a specialist may prescribe synthetic melatonin, as well as light therapy with a medical lamp to use in the morning.RELATED: 20 Things You Shouldn't Do Before BedSleep Problem No. 4: Your legs feel jittery at nightThat creepy-crawly feeling—aptly called Restless Legs Syndrome (RLS)—troubles as many as 1 in 10 people and is thought to be linked to a dysfunction in the way the brain processes the neurotransmitter dopamine. However, in some cases it suggests a nutritional deficiency, Dr. Kryger notes: "With people who have low iron, there seems to be overactivity in parts of the brain that results in an urge to move the legs."Sleep aid: Ice packs, warm packs, massages, a bath—any of these remedies might help, says David N. Neubauer, MD, associate professor of psychiatry at Johns Hopkins University School of Medicine: "Different things seem to work for different people."Also, talk to a sleep doc about trying an RLS drug. Be sure to mention your current prescriptions because some meds (including certain antidepressants) reduce dopamine activity. Get your iron levels checked, too, Dr. Gardner advises: "Sometimes a supplement is the only treatment necessary."Sleep Problem No. 5: You sleepwalk—and even sleep eatFor reasons that aren't completely understood, somnambulists are partially aroused in the night—often from the deepest stage of slumber (called slow-wave)—and proceed to wander around the house. The behavior, which may affect up to 4 percent of the population, appears to run in families and is more likely to occur with sleep deprivation. Another trigger: taking zolpidem (one of the most popular sedatives), according to Robert S. Rosenberg, DO, author of Sleep Soundly Every Night; Feel Fantastic Every Day.Additionally, 1 to 3 percent of people who experience such a zombie-like state actually raid the kitchen. Called sleep-related eating disorder, this condition often strikes women on a diet, who go to bed hungry.Sleep aid: Benzodiazepines (aka tranquilizers) can sometimes help, and so does getting more sleep. As long as your nocturnal adventures don't involve anything risky (like, for example, baking cookies), you may not need medication, Rosenberg says: "Just make sure you safety-proof your home by clearing out clutter and stowing away sharp objects." If you're a nighttime roamer, let your partner know that the ideal approach is to gently lead you back to bed.RELATED: Best and Worst Foods for Sleep

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